Heni Purnama


Background: There are many factors influencing medication adherence among patients with schizophrenia. Medication adherence have an important role in the treatment, especially to preventing relapse patients with schizophrenia. Purpose: The aim of the present study was to examine the relationship between family support and medication adherence among patients with schizophrenia in Bandung, West Java, Indonesia. Method: A cross-sectional study was conducted at the outpatient department of the West Java Province Mental Hospital in Bandung, West Java, Indonesia. Individuals were assessed using the Bahasa versions of Medication Adherence Rating Scale (MARS), and Multidimensional Scale of Perceived Social Support (MSPSS) instruments. Result: A total of 88 patients with schizophrenia were enrolled. The prevalence of medication adherence was 64.8%. By using Chi-square test, the results revealed that family support have no significantly associated with medication adherence Conclusion: This finding could contribute to nursing knowledge to increase the understanding of medication adherence among patients with schizophrenia. The health care providers should promote regarding medication adherence to improve patients’ health status.


Medication adherence, family support, schizophrenia

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Atreja, A., N. Bellam and S.R. Levy. (2005). Strategies to Enhance Patient Adherence: Making It Simple. Medscape General Medicine, 7(1), pp. 4-4.

Boardman, G., T. McCann and D. Kerr. (2014). A Peer Support Programme for Enhancing Adherence to Oral Antipsychotic Medication in Consumers with Schizophrenia. Journal of Advance Nursing. 70(10): 2293-2302.

Brown, M.T. and J.K. Bussell. (2011). Medication Adherence: Who Cares? Mayo Clinic Proceedings. 86(4), pp. 304-314.

Compton, M.T., B.E. Rudisch, P. Weiss, J.C. West and N. Kaslow. (2005). Predictors of Psychiatrist-Reported Treatment-Compliance Problems among Persons in Routine U.S. Psychiatric Care. Psychiatry Research. 1-2.

Dolder, C.R., J.P. Lacro, L.B. Dunn and D.V. Jeste. (2002). Antipsychotic Medication Adherence: Is There a Difference between Typical and Atypical Agents? American Journal of Psychiatry, 159 (1), pp. 103-108.

Fung, K.M., H.W. Tsang and P.W. Corrigan. (2008). Self-Stigma of People with Schizophrenia as Predictor of Their Adherence to Psychosocial Treatment. Psychiatric Rehabilitation Journal. 32(2): 95-104.

Gaebel, W. (1997). Towards the Improvement of Compliance: The Significance of Psycho-Education and New Antipsychotic Drugs. International Clinical Psychopharmacology. 12(1): 37-42.

Gilbert, P.L., M. Harris, L. McAdams and D.V. Jeste. (1995). Neuroleptic Withdrawal in Schizophrenic Patients: A Review of the Literature. Archives of General Psychiatry, 52(3), pp. 173-188.

Hudson, T.J., R.R. Owen, C.R. Thrush, X. Han, J.M. Pyne, P. Thapa and G. Sullivan. (2004). A Pilot Study of Barriers to Medication Adherence in Schizophrenia. The Journal of clinical psychiatry. 65(2): 211-216.

Janca, A., M. Kastrup, H. Katschnig, J.J. Lopez-Ibor, Jr., J.E. Mezzich and N. Sartorius. (1996). The World Health Organization Short Disability Assessment Schedule (Who Das-S): A Tool for the Assessment of Difficulties in Selected Areas of Functioning of Patients with Mental Disorders. Soc Psychiatry Psychiatr Epidemiol, 31(6), pp. 349-354.

Jungbauer, J., B. Wittmund, S. Dietrich and M.C. Angermeyer. (2004). The Disregarded Caregivers: Subjective Burden in Spouses of Schizophrenia Patients. Schizophrenia Bulletin, 30(3), pp. 665-675.

Lacro, J.P., L.B. Dunn, C.R. Dolder, S.G. Leckband and D.V. Jeste. (2002). Prevalence of and Risk Factors for Medication Nonadherence in Patients with Schizophrenia: A Comprehensive Review of Recent Literature. The Journal of Clinical Psychiatry, 63(10), pp. 892-909.

Lama, S., K.V. Lakshmi, P.M. Shyangwa and P. Parajuli. (2012). Level of Compliance and Factors Associated with Non-Compliance to Treatment among the Mentally Ill Patients. Nepal Journals OnLine, Volume 10(2).

Ministry of Health of the Republic of Indonesia. (2013). Basic Health Research 2013 (Riset Kesehatan Dasar 2013). Available Source:, April 17, 2015.

Nursing Department of West Java Province Mental Hospital. (2014). Annual Report. West Java Province Mental Hospital. (Cisarua).

Osterberg, L. and T. Blaschke. (2005). Adherence to Medication. New England Journal of Medicine, 353(5), pp. 487-497.

Rungruangsiripan, M., Y. Sitthimongkol, W. Maneesriwongul, S. Talley and T. Vorapongsathorn. (2011). Mediating Role of Illness Representation among Social Support, Therapeutic Alliance, Experience of Medication Side Effects, and Medication Adherence in Persons with Schizophrenia. Archives of Psychiatric Nursing. 25(4): 269-283.

Sapra, M., I.V. Vahia, P.N. Reyes, P. Ramirez and C.I. Cohen. (2008). Subjective Reasons for Adherence to Psychotropic Medication and Associated Factors among Older Adults with Schizophrenia. Schizophrenia Research. 106(2-3): 348-355.

Suttajit, S. and S. Pilakanta. (2010). Impact of Depression and Social Support on Nonadherence to Antipsychotic Drugs in Persons with Schizophrenia in Thailand. Patient Preference and Adherence. 4: 363-368.

Thompson, K., J. Kulkarni and A.A. Sergejew. (2000). Reliability and Validity of a New Medication Adherence Rating Scale (Mars) for the Psychoses. Schizophria Research, 42(3), pp. 241-247.

Tesfay, K., E. Girma, A. Negash, M. Tesfaye and S. Dehning. (2013). Medication Non-Adherence among Adult Psychiatric out Patients in Jimma University Specialized Hospital, Southwest Ethiopia. Ethiopian Journal of Health Sciences. 23(3): 227-236.

World Health Organization. (2003). Adherence to Long-Term Therapies. Evidence for Action. Available Source:, 20 March 2015.


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